For each therapeutic area, find the following information also with references (link or article)

global patient population, US&China&Europe&Asia patient population, US&China&Europe&Asia market size $$, standard treatment (1st, 2nd, 3rd line of treatment), competition worldwide (which companies sell the drugs, at least 3-5 examples for each, as many as possible), M&A deals for new drugs, some summary of unmet medical needs globally and in US & China, summary of well-known clinical trials, # of new drugs approved by FDA in the past 5 years