Safari Audio Auto-Send Fix

I'm developing an app that requires voice interaction from a mobile phone and a server. The user sends a POST request to the server, which returns both a text response and an audio file to play. We would like to automatically play the audio. However, on Safari, the audio playback fails because it requires direct user interaction for any media action.
I'm looking for support to implement a Safari-compatible solution. I also expect that a true expert can fix the issue in no time.