Prostate Systematic Review & Meta-Analysis

I need a full systematic review and meta-analysis that synthesises all peer-reviewed journal evidence on prostate-related conditions. The scope is strictly medical, so every step—from search strategy through statistical pooling—must align with current PRISMA and Cochrane guidance.

Here’s what I will provide:
• The precise clinical questions and PICOS framework.
• Any key search terms already identified.
• Access to my institutional EndNote account if you prefer to manage citations there.

What I expect in return:
• A reproducible search strategy executed across at least MEDLINE, Embase, and Cochrane Library, limited to peer-reviewed articles only. (Conference abstracts and trial registries are intentionally excluded.)
• A PRISMA flow diagram documenting record identification, screening, eligibility, and inclusion.
• Risk-of-bias assessment using an appropriate tool (e.g., ROB 2 or Newcastle-Ottawa, depending on study designs).
• Data extraction tables covering study characteristics, outcomes, and effect sizes.
• Meta-analysis with pooled estimates, heterogeneity statistics, forest and funnel plots generated in RevMan, R (meta or metafor packages), or Stata—whichever you prefer, provided the code/output are shared.
• GRADE summary of findings and clear narrative interpretation of results.
• A draft manuscript formatted for submission to a urology or oncology journal.

Acceptance criteria:
1. Search strategy and extraction sheet pass independent replication.
2. Statistical code runs without errors on my machine.
3. Final narrative clearly addresses the clinical question and limitations.

If you have completed similar urology or oncology syntheses before, let me know when you can start and roughly how long you’ll need for each milestone (search, screening, analysis, write-up).