Financial analysis

1. What are the business and financing risks associated
with the acquisition of Genentech? Is this a good time
to do the deal?

2. Do you believe the bond issuance will have an
impact on Roche's bond rating?

3. What are the prevailing spreads for non-Roche
bonds? Do you think these spreads are similar to
investor's required yield for the Roche bonds?

4. What is your specific recommendation for the
coupon rate for the Roche 5-year, 10-year, and 30-year
U.S. dollar bonds?

5. What would your coupon rate recommendation be
for the 7-year bond in euro?