Connect to MariaDB database on Synology NAS remotely from SQLalchemy with python

The project is simple, right now I have a problem with connecting to the MariaDB database on my Synology NAS. I would like someone to fix this for me. To have a better understanding of my status now, please refer to this post (https://stackoverflow.com/questions/70016481/connect-to-mariadb-database-on-synology-nas-from-sqlalchemy-in-python-issue ) . The expected delivery will be a working python script (in Jupiter notebook format by using SQLalchemy). Please do expect several attempts to get a successful connection, and thus there will be many rounds of communications. I am in the EU time zone.