Need help in chemistry paper- Design, Discovery and Development of Pharmaceuticals
Budget: £2 – £5 GBP
Morphine (Figure Q26a) is naturally occurring and is commonly used as an opioid analgaesic (Figure Q26a).
(i) List all the asymmetric centres of morphine by using their carbon numbers.
(ii) Describe the therapeutic use of morphine and its undesirable side effects.
(iii) Discuss the possible physicochemical interactions between morphine and its opioid receptor binding site.
(iv) Draw the proposed pharmacophore for morphine and its analogues.
(i) List all the asymmetric centres of morphine by using their carbon numbers.
(ii) Describe the therapeutic use of morphine and its undesirable side effects.
(iii) Discuss the possible physicochemical interactions between morphine and its opioid receptor binding site.
(iv) Draw the proposed pharmacophore for morphine and its analogues.