Bioinformatics knowledge
Budget: $20 – $40 USD
Help in bioinformatics.
What's needed is real knowledge in the following topics:
1) Phylogenetic trees: the iterative algorithm that works on additive matrices only, UPGMA, and Neighbor joining.
2) Protein structures: Levels of protein structure: secondary, tertiary, quaternary structures, Structure prediction: ab initio, homology modeling, threading, Structural alignment: RMSD, superimposition, STRUCTAL method, intra atomic distance matrices
3) Gene expression analysis: Differential expression: upregulation, downregulation, transcription factors, Clustering: K-means, Self-organizing maps (SOM)
4) Biological networks: Types of networks: gene regulatory networks, protein interaction networks, metabolic networks, Topological measures: degree, clustering coefficient, k-core, Analysis of biological networks: The MCODE algorithm, Random Walks on Graphs (with and without restarts)
Please apply only if you have knowledge on all of above.
What's needed is real knowledge in the following topics:
1) Phylogenetic trees: the iterative algorithm that works on additive matrices only, UPGMA, and Neighbor joining.
2) Protein structures: Levels of protein structure: secondary, tertiary, quaternary structures, Structure prediction: ab initio, homology modeling, threading, Structural alignment: RMSD, superimposition, STRUCTAL method, intra atomic distance matrices
3) Gene expression analysis: Differential expression: upregulation, downregulation, transcription factors, Clustering: K-means, Self-organizing maps (SOM)
4) Biological networks: Types of networks: gene regulatory networks, protein interaction networks, metabolic networks, Topological measures: degree, clustering coefficient, k-core, Analysis of biological networks: The MCODE algorithm, Random Walks on Graphs (with and without restarts)
Please apply only if you have knowledge on all of above.