Antisense Oligonucleotide Design for Gene Knockdown

I need a skilled professional to design antisense oligonucleotides (ASOs) for the purpose of gene knockdown targeting a specific gene in mammalian cells.

Key requirements:
- Design ASOs targeting a specific gene
- Expertise in molecular biology and oligonucleotide design
- Experience with mammalian cell systems
- Ability to validate ASO effectiveness

Ideal Skills:
- Background in genetics or biotechnology
- Proficiency in RNA biology
- Previous experience with gene knockdown techniques

Please provide samples of prior work and relevant experience.