Setting Up Prometheus on EC2 Instance

I need an expert in AWS and Prometheus to configure this monitoring tool on my EC2 instance. The setup should be done via direct installation on the instance. In addition to the EC2 instance, I require monitoring for both EC2 and other AWS resources.

Please note, I haven't specified which other resources yet, so your setup should be flexible and comprehensive enough to accommodate future requirements.

Desired Skills and Experience:
- Extensive knowledge of AWS and EC2
- Proficiency in Prometheus installation and configuration
- Ability to monitor multiple AWS resources
- Flexibility and foresight in system setup