Set up methodology for 3D scan analysis in free software such as Blender or Cloudcompare

Someone to set up a methodology and lay out the steps needed to perform geometric analysis on 3D scan mesh files. The scans come from a new (baseline) part and used parts. They're all the same geometry and I'm interested in calculating the volume lost between them. I'm looking for this to be able to get accomplished with free software like CloudCompare or Blender. The deliverable should be a document that summarizes the steps required to achieve this and make it repeatable for hundreds of scans. I'm attaching screenshot of a new and a used part to make it easier to visualize.